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Immunology, Allergology

B lymphocytes and plasma cells

B lymphocytes and plasma cells

B lymphocytes are principal cells that mediate humoral adaptive immunity. After their maturation in the bone marrow, B cells enter peripheral lymphoid tissues, which are the sites of interaction with foreign antigens. Production of antibodies is initiated by the interaction of antigens with a small number of mature B cells specific for each antigen. An antigen binds to the membrane receptors on specific B cells and initiates a series of responses that lead to two principal changes: cell proliferation resulting in expansion of the clone, and differentiation to either plasma cells actively secreting antibodies or to memory cells.

Key words: B cells, subsets of B cells, memory B cells, plasma cells

 
author: Milan Buc | LF UK v Bratislave | discipline: Immunology, Allergology | category: Lectures, Presentations | keywords: B cells, B cell subsets, memory B cells, plasma cells | attachment: 1 | viewed: 1022x | published on: 6.3.2017
 

Immunology for student of general medicine

Immunology for student of general medicine

This is a presentation of lectures of the subject „Immunology“ for students of general medicine. It covers basic aspects of theoretical immunology, immunopathological states, immunological aspects of transplantation and immune response to tumours. Also immune reaction to microbes and principles of vaccination are covered. The course includes basic information of immunological laboratory methods and their interpretation as well.

 
author: Jiří Litzman | LF MU | discipline: Immunology, Allergology | category: Educational works, Presentations | keywords: general medicine, immunology, immunopathological states | attachment: 17 | viewed: 3108x | published on: 6.9.2013 | last modified on: 10.10.2013
 
SCHWARZ Daniel, DUŠEK Ladislav. A uniform platform for electronic publishing and sharing the educational content in the network of medical faculties MEFANET [online]. Masaryk University, [2008], [cited 2018-01-23]. Available from WWW: <http://portal.mefanet.cz>. Version 1.9 [2014].