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CYTOCHROME P-450: genetic and population aspects

CYTOCHROME P-450: genetic and population aspects

Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm. The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.

Mavlyanov I.R., Ashirmetov A.Kh., Mavlyanov Z.I., Jarilkasinova G.J.: CYTOCHROME P-450: genetic and population aspects, Pavol Jozef Šafárik University in Košice, Košice 2017, ISBN 978-80-8152-526-1.

 
author: Iskander Rahimovich Mavlyanov, Abdurashid Khamidovich Ashirmetov, Zafar Iskandarovich Mavlyanov, Gavhar Januzakovna Jarilkasinova | UPJŠ LF v Košiciach | discipline: Biology, Pharmacology, Medical Chemistry and Biochemistry | category: Educational works | keywords: cytochrome P-450 | attachment: 2 | viewed: 138x | published on: 5.12.2017 | last modified on: 23.3.2018

Basic principles and molecular mechanisms regulating early development of mammals - physiology and pathology

Basic principles and molecular mechanisms regulating early development of mammals - physiology and pathology

This educational text titled “Basic principles and molecular mechanisms regulating early development of mammals - ¬physiology and pathology“ describes how embryogenesis proceeds in mammals. In this text, students will learn how the egg is fertilised, how the fertilised egg survives in the mother’s womb (called implatation), how the fertilised egg divides, how the blastocyst develops, how the implanted blastocyst undergos gastrulation or the three germ layers form, and how the brain, heart, muscle, and internal organs develop. Moreover, if the processes go awry, what the baby will be affected. This educational material is recommened to General Medical, Dental Medical students and the students who are taking a developmental biological course.

 
 

Neural development and embryonic stem cell-based developmental modelling

Neural development and embryonic stem cell-based developmental modelling

This educational article titled “Neural development and embryonic stem cell-based developmental modelling“ describes how to investigate the roles of genes in human neural development using stem cell technologies and molecular biology techniques. This educational article is primarily focused on experimental practices. Thus this article is intended for postgraduate students (e.g. Master student, Diploma, and PhD students). However, the article is also suitable for undergraduate students, who are interested in stem cell biology and molecular biology. In the text, students will learn how to perform basic molecular biology techniques (e.g. gene cloning, making fusion protein, PCR and sequencing), and how to grow and to manipulate human embryonic stem cells (hESCs). Moreover, students will learn how to drive hESCs toward to neural fates.

 

Analysis of genomic and proteomic data

Analysis of genomic and proteomic data

This e-learning educational textbook is dedicated to analysis of data from genomic and proteomic high-throughput experiments, such as microarrays, MASS spectrometry, 2-D gel eletrophoresis and DNA sequencing.The book discuss all the important analytical steps from pre-processing through differential gene(protein)-expression to pathways and meta-analysis of multiple experiments. Interactive examples in R and lectures in video format are provided. This educational material contains contributions of different experts in the field from all over the Europe. The content in this e-learning material will be up-dated and extended so that it reflects the latest knowledge in this field.

 

 
author: Eva Budinská | LF MU | discipline: Biology, Genetics, Medical Informatics and Information Science | category: Educational works, Educational websites | keywords: genomics, proteomics, gene expression, dna, microarray, data analysis, regression, prediction | attachment: 1 | viewed: 4103x | published on: 13.1.2010
 
SCHWARZ Daniel, DUŠEK Ladislav. A uniform platform for electronic publishing and sharing the educational content in the network of medical faculties MEFANET [online]. Masaryk University, [2008], [cited 2018-06-18]. Available from WWW: <http://portal.mefanet.cz>. Version 1.9 [2014].