Results found: 11810
... page If there is suspicion of a zoophilic infection and the veterinarian finds no clinical lesions, the whole fur coat of the suspected animal should be brushed with a sterile comb which is then pressed on the agar. Here a „healthy“ cat from a family affected by microsporia… …and massive growth of Microsporum canis from the fur of the animal ...
1.LF UK | discipline: Dermatology | ...: Array | published on: 12. 1. 2007
It is a heterogeneous group of tumors with tumors with various histological subtypes that differ in response to treatmevarious histological subtypes that differ in response to treatment and in the nt and in the prognosis of the disease ... The most important clinical significance had finding of combinedThe most important clinical significance had finding of combined deletion 1p36/19q13 in patients with deletion 1p36/19q13 in patients with oligodendroglialoligodendroglial tumourstumours, which is , which is considered to be a predictor of good response to chemotherapy anconsidered to be a predictor of good response to chemotherapy and fair prognosis ...
1.LF UK | discipline: Haematology | ...: Array | published on: 8. 12. 2006
In addition to immediate reaction after allergen entry, atopy is characterised by a late phase reaction. It is mediated by an inflammatory infiltrate of eosinophils, basophils, neutrophils, and TH2 lymphocytes ... Their treatment is based on a neutralisation of histamine, leucotrienes, IgE antibodies and suppression of ongoing inflammatory reactions by glucocorticoids ...
LF UK v Bratislave | discipline: Immunology, Allergology | keywords: Allergy, anaphylaxis, atopy, IgE antibodies, histamine | published on: 4. 4. 2012
The enzyme catalase is a hemoprotein containing 4 molecules of haem. It is found in the blood and liver ... The blood catalytically degrades hydrogen peroxide to form molecular oxygen (a catalase activity) or transfer oxygen of peroxide to the other substrates (a pseudoperoxide activity) ...
UPJŠ LF v Košiciach | discipline: Medical Chemistry and Biochemistry | ...: Array | published on: 16. 9. 2013
Albumin significantly contributes to maintaining blood oncotic pressure and pH. A significant decrease in albumin can lead to edema due to water leakage from blood vessels ... Mix and measure the absorbance of the analyzed sample and standard against the blank sample in a 1 cm cuvette, at a wavelength of 595 nm. 3 ...
• After exposure to autoantigen during fetal life autoreactive clones are eliminated ( „forbidden clones“). • If a concrete cell recognizes its specific antigen, it is stimulated, proliferates and forms a clone = clonal selection ... • After repeated divisions the cell becomes a terminally differentiated cell, that does not proliferate and after some time dies ...
LF MU | discipline: Immunology, Allergology | ...: Array | published on: 6. 9. 2013
... slide-master-content slide-content Acute mania Depressive sy with agitation Acute severe anxiety: verbal contact (mostly a directive approach), slow controlled breathing ... Depression 2-3 times more often in somatically ill patients 1. Comorbidity of a somatic illness 2. Symptomatic depression (organic) (DM...) 3 ...
UPJŠ LF v Košiciach | discipline: Psychiatry, Psychology, Sexology | ...: Array | published on: 7. 5. 2024
BASIC TERMS page • the principle of a biometrics is known for many years • the commercially available devices used from the late 1960s • technological development together with broad scale of applications • adoption in specific application areas (military, government, public services etc ... ) • used primarily for access control purposes • effect of various factors: • best practice in testing • standards for interfaces to devices • general interoperability • human responsibility/factors • environment • general infrastructure • use of mobile devices brought new expansion of biometrics • help to secure access to the devices and also to transactions undertaken via such devices BASIC TERMS page Biometrics • science dealing with measurement and statistical analysis of people's physical and behavioural characteristics Biometric technologies • technologies based on automated methods used mainly for identification and access control, or for identifying individuals that are under surveillance • the basic premise of biometric authentication is that everyone is unique and an individual can be identified by his or her intrinsic physical or behavioural traits or attributes Biometric screening • measurement of physical characteristics (e.g. height, weight, body mass index, blood pressure, waist circumference, blood cholesterol, blood glucose, aerobic fitness tests etc.) that can be taken, e.g. at the work site and used as part of a workplace health assessment to benchmark and evaluate changes in employee health status over time • the goal of implementing biometric screenings is to reduce health risks, improve health status, reduce health care costs, and improve the productivity and performance of the workforce BASIC TERMS page Biometric system • a pattern recognition system that recognizes a person by comparing the binary code of a uniquely specific biological or physical characteristic to the binary code of the stored characteristic • samples are taken from individuals to see if there is similarity to biometric references previously taken from known individuals • specialized mathematical algorithms are applied to the sample and compared to the template sample to determine if the individual can be recognized • system must be able to identify a person based on one or on combination of biometric identifiers (quickly, automatically, with no human intervention) • recognition in order to: • determine the identity of the person = identification • validate claimed identity = verification Identity management • registration, storage, protection, and utilization of user’s personal identifier(s) and privilege(s) in an secure electronic environment BASIC TERMS page General levels of identification (when providing person’s identity, often referred to identity management functions, recognising a user, Who I am?) ...
UPJŠ LF v Košiciach | discipline: Medical Informatics and Information Science | ...: Array | published on: 11. 10. 2010
At first prepare the Uffelmann reagent: to 1 ml of the phenol solution in a test tube add 1 drop of iron (III) chloride solution ... Hydrogen peroxide formed is used as a substrate for peroxidase (POD) that catalyzes the reaction 2H2O2 O2 + 2H2O ...
UPJŠ LF v Košiciach | discipline: Medical Chemistry and Biochemistry | ...: Array | published on: 15. 2. 2011
Liver biopsy Hepatomegaly - diagnosis page Standard blood tests • Blood count + blood smear • Liver enzymes: AST, ALT, ALP, GMT • Bilirubin (direct and indirect) • Albuminemia (prealbumin) – protheosynthesis • Hemocoagulation ex. – prothrombin time • (Quick) disorders of production of hemocoagulation factors cholestasis (vitamin K deficiency) disorder of protheosynthetic ff.of hepatocytes page Standard blood tests • 2 true „liver function tests“ are measurement of serum albumin and PT asses the synthetic function of the liver directly, helpfull in monitoring response to Th , suggest prognosis • presence of hyperbilirubinemia in patient with H. suggests: • cholestasis or hemolytic disease • Cholestatic d elevation of conj.Bi, GMT and ALP • Bi can be fractionated to distinguish between hepatic dysfunction (conjugated/direct Bi) and hemolytic disease or congenital disorder of Bi metabolism(unconjugated/indirect Bi) page Standard blood tests • Hepatocellular injury results in a predominant rise in hepatic aminotransferases suggests a viral or toxic insult • ALT is more liver specific than AST (other organs) • the degree of aminotransferase elevation does not correlate well with clinical prognosis • declining aminotransferase levels may indicate a decrease in functioning hepatocytes from ongoing necrosis page • ELFO (liver cirrhosis - ↓ albumin, ↑α fraction, fractions β a γ („block“ β – γ) • Ig – quantitative ex ... page Diagnostic algorithm to arrive at the most common dg for a child older than 1y ako 1 rok page Spleen - anatomy Largest organ of the mononuclear-phagocyte system (MPS) Size : 11 - 12 x 7 x 3 cm Weight: 100 – 150 g Volume: 250 ml page Spleen - physiology Functions of spleen: 1 ...
UPJŠ LF v Košiciach | discipline: Paediatrics, Neonatology | ...: Array | published on: 22. 3. 2017
... to monitor the course of disease RarelyMostly page A person has been in contact with an infectious agent Even with high levels of Ab person can be healthy Detection of Ab = determining a complete diagnosis (presence of MIO in organism) ? ... This stripe will retain the beads that have bound Ag. A third control stripe binds any beads. Color developing at the test line = positive test ...
UPJŠ LF v Košiciach | discipline: Microbiology | ...: Array | published on: 28. 5. 2023
Term ANATOMY from Greek anatomé = „a cutting up“ SYSTEMATIC ANATOMY As a science deals with morphology and structures of the human body. Its sound knowledge forms a basis for understanding of other subdivisions of the anatomy and is required to all clinical medical specialties ...
LF UK v Bratislave | discipline: Dentistry | keywords: Topographic anatomy, head, neck, cranium | published on: 13. 10. 2015
Medical Faculty of Masaryk University Brno Department of Paediatrics, University Hospital Brno page Paediatric Cardiology - Congenital Heart Defects - Arrhythmias - Inflammatory heart disease - Cardiomyopathy and other cardiac disease (tumors, metabolic disease) page CONGENITAL HEART DEFECTS Prevalence 6-10/1000 liveborn Etiology of CHD A genetic disorder is a disease caused in whole or in part by a change in the DNA sequence away from the normal sequence. Genetic disorders can be caused by: - a mutation in one gene (monogenic disorder), - by mutations in multiple genes (multifactorial inheritance disorder), - by a combination of gene mutations and environmental factors, - or by damage to chromosomes (changes in the number or structure of entire chromosomes, the structures that carry genes) Non-genetic Genetic page Down syndrome Patau syndrome Edwards syndrome Turner syndrome Williams Beuren syndrome Alagille syndrome Holt-Oram syndrome Marfan syndrome 22q11 deletion – Di George syndrome Congenital heart defects + syndromes page - Clinical evaluation - ECG - Chest X ray - Echocardiography - Cardiac catheterization - CT angiography - MRI Diagnosis ? ...
LF MU | discipline: Cardiology, Angiology | ...: Array | published on: 23. 10. 2020
• random trial can be repeated (theoretically in unlimited number of trials) Random variable – has various values depending on a chance • if the random variable (trial) will be labeled as 𝑿 then its values (results) will be 𝒙𝒊 where 𝒊 = 𝟏, 𝟐, 𝟑…𝒏 𝑿 = 𝒙𝟏, 𝒙𝟐, … , 𝒙𝒏 𝒙𝒊 present simple events (can not occur together, but one has to be the result of the trial) Random event is an arbitrary statement about the result of random trial and represents a group of simple events • examples: • the result of coin toss will be the „head“ • if a fair six-sided die is rolled the face 6 will be observed • the new-born will be boy • product will be faulty piece • there will be more than 10 patients in the waiting room ... THEORY OF PROBABILITY page If the group of all possible results in random trial is known then it is possible to state a chance to get certain result of the trial ...
UPJŠ LF v Košiciach | discipline: Medical Informatics and Information Science | ...: Array | published on: 9. 10. 2019
UPJŠ LF v Košiciach | discipline: Medical Informatics and Information Science | ...: Array | published on: 11. 12. 2009
The glucose is a unique energy substrate: • is the only material from which energy can be obtained even in the absence of oxygen (hypoxia) and without mitochondria; erythrocyte (cells lack mitochondria) are glucose-dependent • it is the sole source of acetyl CoA as a substrate for the citric acid cycle, for some tissues, eg ... Hydrogen peroxide formed is used as a substrate for peroxidase (POD) that catalyzes the reaction 2H2O2 O2 + 2H2O ...
) • seasonal associations – greater incidence in autumn and winter • dietary factors – cow´s milk, nitrates page Enviromental factors Accelerators • stress • infection • cold weather • rapid growth Factors, which decrease risk of T1D • breast-feeding, hypoalergic formula • diet in the 1st year of life • adequate vitamin D intake page Pathogenesis – autoimmune injury Target autoantigens • several autoantigens were recognised within the pancreatic ß-cells that may play important roles in the initiation or progression of autoimmune islet injury • insulin (IAA) – most important autoantigen • glutamic-acid decarboxylase (GAD) • insulinoma-associated protein 2 (IA-2) • autoantigen ZnT8, (zinc transporter 8 of islet ß-cells) page Progress of the diabetes not enough insulin glucose is unable to move into the cells system of body „starvation“ occurs blood glucose level rise glycosuria, osmotic polyuria, polydipsia TYPICAL CLINICAL SYMPTOMS page Presentation of T1D • at the onset of symptoms about 10% of beta cells are viable • classic symptoms present for a few days to several weeks • diabetic ketoacidosis DKA at diabetes onset varies widely by geographical location • DKA is more frequent: - in infants, toddlers and preschool-aged children - in children, who do not have a first degree relative with T1D - in children whose families are of lower socioeconomic status page Onset of T1D without DKA older children and adolescents • polyuria (due to the glucose-induced osmotic diuresis) • polydipsia (due to the increased urinary losses) • fatigue • weight loss • nocturia, secondary enuresis • vaginal or cutaneous moniliasis • blurred vision The earliest symptoms are related to hyperglycemia page Onset of T1D without DKA Infants, toddlers • the diagnosis is more difficult because the patients are not toilet trained and they cannot express thirst • polyuria may not be detected and polydipsia is not apparent • common findings are: decreased energy and activity, irritability, weight loss, and physical signs of dehydration • severe Candida diaper rash • unexplained metabolic acidosis, hypovolemia, tachypnoea should highten the suspicion for diabetes page A number of other clinical findings may be seen: • polyphagia, anorexia, nausea, vomiting, abdominal pain, which at times can mimic appendicitis (child can undergo a surgery!) ... ) • low C-peptide/insulin • high glycated hemoglobin Laboratory evaluation of fluid and electrolytes disturbance • biochemistry (serum Na, K, P, osmolarity, kidney function, lipid status..., urine – glucose, ketone) • blood count • acid base page T1DM – initial management • children with signs of severe DKA or in risk of cerebral edema (<5 years of age) should be treated in a pediatric intensive care unit The initial goals of management are: 1 ...
UPJŠ LF v Košiciach | discipline: Paediatrics, Neonatology | ...: Array | published on: 27. 3. 2017
Boil the content of the test tube no. 1 in a boiling water bath and then cool it down. 4 ... Mix well all test tubes. 6. Add a layer paraffin oil onto the mixture levels in test tubes to keep anaerobic conditions. 7 ...
) • Hallucinations - mainly in elderly people, probably primarily as a result of long-term use of dopamine agonists • In young people - tendencies to uncontrolled behavior - gambling, hypersexuality ... v=vWWnQErrmpg page Chorea minor https://www.brainandlife.org/a rticles/sydenham-chorea-st- vitus-dance-name page Huntington chorea • inerited neurodegenerative disease Etiology • The function of the HTT gene, which encodes the protein huntingtin, is an autosomal dominant inherited mutation ...
UPJŠ LF v Košiciach | discipline: Physiology and Pathophysiology | ...: Array | published on: 8. 4. 2024
Department of Child Surgery, Orthopedics and Traumatology , TH Brno page Diagnosis 1 • eutrophic newborn, PNV 51cm/3450g • prenatally: polyhydramnios • postnatally: • excessive salivation • a cough while first drinking • Cyanosis • aspiration page Diagnosis 1 • Put gastric probe IMPOSSIBLE, collides with resistance page Diagnosis 1 • Thorax and abdomen X-ray page Diagnosis 1 • X-ray examination with contrast (what ?) ... page VACTERL syndrome - vertebral - anorectal (10%) - cardiovascular (25%) - tracheal - esophageal - renal (10%) - limb V A C T E R L page Classification page Operative technique When do we operate ? ...
LF MU | discipline: Surgery, Traumatology and Orthopaedics | ...: Array | published on: 26. 10. 2018
• Conservative • Ambulatory care (1st, 2nd a st., 2nd b st. of smaller range) • Hospitalized care • Surgical 3rd sl ... Usually during hospitalization, small surfaces can be solved as a day case. • Primary examination is the same as the 2nd stage burns primary examination 17th sl ...
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UPJŠ LF v Košiciach | discipline: Medical Ethics and Law | keywords: copyright, personal data protection | published on: 29. 2. 2008
It is reported to be a significant substance with antioxidant effects, representing 35 to 65% of the total plasma antioxidant capacity ... After deproteinization of the biological material (with trichloroacetic acid), uric acid reduces the Folin-Ciocalteu reagent (in the presence of sodium carbonate) to a yellow-green compound, the absorbance of which can be measured at a wavelength of 610 nm ...
Is there a member of the „family“ with a similar condition to that being complained of by the child? Does any member of the „family“ have a disability, and have there been any deaths in childhood? ...
UPJŠ LF v Košiciach | discipline: Paediatrics, Neonatology | ...: Array | published on: 29. 9. 2016
... page B 35.0 Tinea of the scalp and beard Kerion Celsi – a deep form of tinea of the scalp with purulent infioltrates. Differentiation from a bacterial infection (carbuncle) is difficult ...
... page Meconium ileus page Meconium ileus page Meconium ileus page Meconium ileus page We are having a baby it could happen to you as well page Is it going to be smooth? ... colar bone fr., ABC functions unstable • Exercising according to neurophysiology – connection between movement and nervous system – Vojta´s method • Well conducted exercising for 4x day • Baby crying – suppression of personal freedom manifestation, no pain • If the elevation of UL fails within a period of next 3 months – mostly never successful • 90% of the disabled in 1 year is without neurological deficiency page The goal of our work is being sincerely interested in our entrust patients, have a friendly relationship with them, treat them with kindness ...
) flanked by direct repeats (transposon-like) enabling movement in chromosome and horizontal transfer to new bacterial cells (by plasmid, phage, conjugative transposon) nonpatogenic bacteria that require PAI become pathogenic (Salmonella ≥ 5) chromosome or plasmid ↘ page Extrachromosomal genetic elements plasmids bacteriophages (prophages) page Plasmids double-stranded, usually circular, contain 5-100 genes: a) self replication genes b) genes providing selective advantage under a given environmental state (resistance to ATB, virulence factors...), not essential for survival separated from chromosome and replicate independently of the chromosome 1-1000 kbp, number of identical plasmids in a single cell varies (small – max. 50, big - few) they can be removed from the cell (↑t, mutagens, passage) 1 ... (Staphylococcus, Bacillus, Corynebacterium, Lactobacillus), G- (E. coli) • Phage DNA can be cleaved inaccurately from chromosome with host genes → DNA can be: a) integrated into chromosome b) degraded c) unintegrated in cell 2 ...
UPJŠ LF v Košiciach | discipline: Microbiology | ...: Array | published on: 21. 5. 2023
Sacrum, Internal iliac artery Pelvic diaphragm: Levator ani muscle, Coccygeus muscle Urogenital diaphragm Pudendal nerve Common iliac vein, external and internal iliac vein Innervation of pelvic organs Regional lymph nodes of the pelvis Internal iliac artery PARIETAL BRANCHES: iliolumbar artery lateral sacral arteries obturator artery (gives off the pubic branch, which forms a corona mortis) superior gluteal a. inferior gluteal a. VISCERAL BRANCHES: umbilical artery (gives off superior vesical arteries, has patent part and ocluded part distally, continues as medial umbilical lig.) ...
UPJŠ LF v Košiciach | discipline: Anatomy | ...: Array | published on: 30. 6. 2018
... page Genetic aspects of atopy • Probability of atopy in a child : – Both parents atopics: 80%, – One parent atopic: 50%, – No patent is atopic: 15% ... page page Tuberculin reaction page Examples of diseases where type-IV hypersensitivity plays a key role • Contact exzema • Cavitation in tuberculosis • Sarcoidosis • Several types of vasculitis • Autoimmune diseases where T- lymphocytes play a major role ( multiple sclerosis) page Contact dermatitis due to nickel hypersensitivity Zdroj obrázku: Allergy Capital: Contact dermatitis ...